Piperacillin sodium salt

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

哌拉西林是一种半合成、广谱、氨苄青霉素衍生的脲青霉素抗生素，建议用于假单胞菌感染。

Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.

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Animal Model:BALB/c low inoculum model of K. pneumoniae, KEN-11 strain Dosage:100 mg/kg Administration:Intravenous injection (i.v.), 4 times a day, 5 d, in combination with Tazobactam (12.5 mg/kg, i.v., 4 times a day, 5 d)Result:Enabled all mice survived whereas all control mice died by 5 d, decreased the number of bacteria in lungs compared with control group[. Observed no bacteria in the blood of most mice (except for two mice at the early phase) while bacteria were observed in the blood of control group. Observed few inflammatory cells in the alveoli whereas an influx of numerous inflammatory cells were observed in the control group.

CL 227,193 | T-1220

Microbiology/Virology

Antibiotic

β-Lactamase

Infection

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59703-84-3

539.54

C23H26N5NaO7S

>98% (HPLC)

Ethanol: 100 mg/mL (185.34 mM); Water: 100 mg/mL (185.34 mM); DMSO: 100 mg/mL (185.34 mM)

CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+]

sodium;(2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

(-20℃)

With Ice Pack

≥ 2 years